TBHQ in Food: Side Effects & Dangers

05 Feb.,2024

 

TBHQ is used in food as a preservative, so it's found in hundreds of processed foods.

TBHQ has been linked to numerous side effects, including DNA damage, nausea, liver effects, and possible mutation in cells.

TBHQ should be avoided because of its potential carcinogenic effect.

It’s Friday, and you’re unwrapping peanut butter cups to have a little sweet delight after a hard day’s work. However, after giving a glimpse at the ingredients list, you find an interesting component: TBHQ.

This harmless-looking chemical that can be found in a frightening amount of our beloved foods, including Mcdonald’s french fries, Chicken McNuggets, Butterfinger, Eggo Waffles, Little Debbies, and pop-tarts, is tert-Butylhydroquinone (also called TBHQ or tertiary butylhydroquinone), a synthetic compound that is used widely in the food industry as an antioxidant to prevent the food from rotting.

But besides lurking in our food, it’s also used in biodiesel, resins, lacquers, and varnishes.

TBHQ is common not only in the US but also in Europe where it’s classified with an E-number 319. The substance has been evaluated by both the European Food Safety Authority (EFSA) and the United States Food and Drug Administration (FDA), who have found TBHQ to be safe to consume up to a certain amount. 

Higher doses, however, can be fatally serious as studies have linked TBHQ to stomach tumors and DNA damage. The Center for Science in the Public Interest recommends people avoid the substance because of its possible carcinogenic effect.

What Is TBHQ?

TBHQ can often be seen listed as an antioxidant, which makes it sound healthy. We all need antioxidants, so why doubt TBHQ?

TBHQ isn’t a natural antioxidant though, not the kind that’s found in natural food sources. It’s a synthetic chemical that has antioxidant properties, it’s not an actual antioxidant, as also pointed out by Dr Axe. The main goal of this chemical is to prevent fats and oils from oxidating, hence extending the shelf life. Because of this quality, TBHQ is used in various processed foods.

The National Institute of Health has defined TBHQ as a “white to tan, crystalline powder that’s soluble in water and is used as an antioxidant in food, in cosmetics, and as a chemical stabilizer”.

TBHQ is a legal synthetic compound, but whether it’s entirely healthy to consume or not is a different question. The substance hasn’t been very thoroughly studied yet, but one thing is sure: it’s not completely safe.

TBHQ is not a naturally occurring substance. The compound is similar to butyl molecules, which are found in the lighter fluid. TBHQ itself isn’t, of course, butane, but it does share a similar molecular structure. All-in-all, it’s a man-made substance that has little to do with actual antioxidants.

How Much TBHQ Is Safe to Consume?

FDA has set a maximum limit for TBHQ of 200mg/kg in foods. The acceptable daily intake (ADI) is said to be 0.7 mg/kg/day. That means a 150-pound person could easily consume even 48 milligrams of TBHQ.

However, WHO has said that many people actually exceed the limit, consuming even as much as 180 percent of the daily allowed intake limit. 90 percent of Americans hit the ADI on a daily basis.

The safe consumption limit isn’t actually entirely clear. While the 0-0.7 mg/kg limit has been the recommended one for some time, Dr. Mercola brought out an interesting discrepancy: the Codex Commission set the limit to as much as 400 mg/kg, depending on the food.

This massive difference points to uncertainty as you can’t really be sure how much is safe to consume.

What Does TBHQ Do to Your Body?

While the limit seems to be uncertain, you definitely don’t want to play hooky when it comes to consuming TBHQ in food.

The book “A Consumer’s Dictionary of Food Additives” has brought out the harmful TBHQ side effects. The horrific truth is this: consuming as little as one gram of this substance, can cause:

  • nausea, vomiting
  • a ringing feeling in the ears
  • delirium
  • sense of suffocation
  • collapse

Beyond these issues, the substance has been linked to a variety of health hazards:

  • liver effects and biochemical changes even at very low doses
  • reproductive effects
  • possible mutation in cells

TBHQ has even been linked to increased food allergies.

The biggest issue is related to the substance’s possible cancerous effect. Studies have shown that long-term consumption of TBHQ can develop cancerous precursors in the stomach and even cause DNA damage.

Moreover, the substance can make cancer cells more resistant to chemotherapy, making the issue especially complicated.

Since the FDA allows TBHQ to make up a maximum of 0.02 percent of the oils in food, it means that it’s luckily fairly hard to hit even the 1-gram point, so it’s relatively difficult to develop TBHQ toxicity. For example, it would take 11 pounds of McNuggets to actually get to 1 gram of TBHQ.

However, TBHQ is not always marked on food labels, so you might not always know where it’s lurking. 5 grams of TBHQ can even be lethal. Since it’s hard to consume so much TBHQ, it’s considered to be a safe substance.

The main question is though, should your food include any such substances at all? Should you put man-made chemicals in your body, especially if they’re proven to be possibly carcinogenic? Are chicken nuggets or peanut butter cups really worth it?

The good news is that TBHQ is water-soluble, so it doesn’t accumulate in your body. This means that the possible toxicity is related to current consumption, not the consumption of TBHQ over time.

TBHQ Side Effects

To put things into perspective, there’s not awfully much research about TBHQ side effects yet, but from what’s available, things aren’t looking good.

Here are some of the dangerous things TBHQ can do to your body:

Damaged Immune System

According to Dr. Axe, TBHQ might interfere with your body’s immune system, making it harder for you to deal with illnesses. The main problem is that TBHQ seems to cause one specific protein called Nrf2 to interact with our immune responses in a negative way, making our bodies more susceptible to illnesses.

Potential Cancerous Effect

As mentioned above, TBHQ has been linked to a possible cancerogenic effect. Research has shown that the substance can promote the growth of cancer cells, it might increase the cancer cells’ longevity, and even make the body more resistant to chemotherapy.

Some studies have proven the opposite, but it’s unclear whether it depends on the type of cancer cells or something else. The cancer risk still remains, though.

Possible Neurological Issues

TBHQ consumption has been related to several neurological problems. For example, The National Institute of Health has recorded symptoms like vision disturbance and medulla paralysis, both of which are serious neurological issues.

Might Increase Food Allergies

Cheryl Rockwell, Ph.D., from Michigan State University, conducted research related to how TBHQ might interact with our immune system. It was found that even low doses of TBHQ might increase our body’s response to allergens, increasing the possibility of hypersensitivity.

Might Cause Allergic Contact Dermatitis

Besides possible food allergies, it has been found that TBHQ that’s found in cosmetics, might also cause allergic contact dermatitis. Therefore, it’s wise to stay away from TBHQ, even if it’s just in your lipstick or hair dye.

What Foods Contain TBHQ?

Since TBHQ’s main point is to help to preserve food, it’s mostly found in processed foods. Sadly though it’s not always marked on the label so it’s quite possible to not even know about the substance’s presence.

Mostly, TBHQ is found in the following foods:

  • processed fats
  • canola oil
  • frying and cooking oil at many fast food places
  • packaged foods
  • frozen fish products
  • soft drinks
  • some soy milk products
  • some butter and margarine products
  • some microwave popcorn brands
  • many processed foods like some cereals, sweets, crackers, breads
  • some peanut butter products
  • many ramen noodles

Beyond food, TBHQ can be found even in lipsticks, hair dye, many resins, varnishes, and some pet food products.

How to Avoid TBHQ in Food?

As TBHQ is water-soluble, all possible dangers will disappear once you stop consuming the substance.

A good rule of thumb to follow is to avoid processed foods, especially processed fats. There are tons of natural, healthy alternatives, especially when it comes to antioxidants. Dr. Axe recommends the following natural antioxidants instead of eating foods that contain TBHQ:

  • olive extracts
  • sesame oil extracts
  • sunflower oil extract
  • rosemary oil extract
  • cinnamon oil
  • clove oil
  • citrus extract
  • green tea extract

Whenever you see TBHQ in food, keep in mind the possible side effects. Even if it’s safe to consume in certain amounts, it’s better to opt for fresh healthy foods, instead of consuming processed unhealthy fats that won’t do you any good anyway, despite their TBHQ content. Fresh is the best, and there’s no better food than a home-cooked one.

TBHQ is another possibly dangerous substance you can avoid if you keep fast food and processed products out of your body.

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